Pharmacological treatment is not ordinarily indicated for patients with methamphetamine or cocaine dependence. In addition, no pharmacotherapies have FDA indications for the treatment of methamphetamine or cocaine.[1] Pharmacological treatments which include opioid agonists and opioid antagonists, however, are commonly used to address heroin and other opioid dependence. (An opioid agonist is a drug that has a similar action to morphine. An opioid antagonist blocks or otherwise counteracts the physiological and/or subjective reinforcing effects of an opioid.)